• Lufthansa German Airlines Germany
• Aero-flot Airline – Russia
• Pan American World Airways System – S.A.
• Trans-world Airways – S.A.
• Delta Airlines – S.A.
• Thai Airways International – Thailand
• Swissair – Switzerland
• Emirates – A.E
• Air-Ceylon – Sri Lanka
• Iberia – Spain
• Pakistan International Airlines – Pakistan
• Braathens – Norway
• Scandinavian Airlines System – Norway
• KLM Royal Dutch – Netherlands
• Royal Nepal Airlines – Nepal
• Japan Airlines – Japan
• All Nippon Airways – Japan
• Alitalia – Italy
• Ryanair – Ireland
• Garuda Airways – Indonesia
• Air-India – India
• Cathay Pacific – Hong Kong
• Air France – France
• Finnair – Finland
• Easy Jet – England
• O.A.C. – England
• Sabena – Belgium Qantas
• Empire Airways – Australia
• Araina Afghan Airlines – Afghanistan

Here is a list (as on 2020-04-03) of the 100 biggest airlines based on the number of departures (and not the number of passengers). The number of flights is the daily average for one week.

1 – American Airlines – 5961 flights every day
2 – Delta Air Lines – 4290 flights every day
3 – United Airlines – 4048 flights every day
4 – Southwest Airlines – 3795 flights every day
5 – Ryanair – 2151 flights every day
6 – easyJet – 1785 flights every day
7 – China Southern Airlines – 1781 flights every day
8 – China Eastern Airlines – 1716 flights every day
9 – IndiGo – 1665 flights every day
10 – Turkish Airlines – 1379 flights every day
11 – Air Canada – 1325 flights every day
12 – Air China – 1244 flights every day
13 – ANA – 1224 flights every day
14 – Alaska Airlines – 1119 flights every day
15 – LATAM Airlines – 1111 flights every day
16 – Air France – 1010 flights every day
17 – Aeroflot – 938 flights every day
18 – JetBlue Airways – 921 flights every day
19 – JAL – 825 flights every day
20 – British Airways – 782 flights every day
21 – Lufthansa – 720 flights every day
22 – KLM – 675 flights every day
23 – Qantas – 668 flights every day
24 – Shenzhen Airlines – 664 flights every day
25 – Gol – 660 flights every day
26 – Spirit Airlines – 646 flights every day
27 – Lion Air – 639 flights every day
28 – Wizz Air – 636 flights every day
29 – Vueling – 627 flights every day
30 – Azul – 620 flights every day
31 – Xiamen Airlines – 589 flights every day
32 – SpiceJet – 583 flights every day
33 – AirAsia – 583 flights every day
34 – WestJet – 575 flights every day
35 – AVIANCA – 575 flights every day
36 – Hainan Airlines – 568 flights every day
37 – Sichuan Airlines – 523 flights every day
38 – Shandong Airlines – 485 flights every day
39 – Saudia – 478 flights every day
40 – Emirates – 463 flights every day
41 – Air India – 457 flights every day
42 – Pegasus – 446 flights every day
43 – Garuda Indonesia – 439 flights every day
44 – Qatar Airways – 429 flights every day
45 – Wings Air – 426 flights every day
46 – Volaris – 398 flights every day
47 – Alitalia – 393 flights every day
48 – Aeromexico – 390 flights every day
49 – S7 Airlines – 389 flights every day
50 – Air New Zealand – 383 flights every day
51 – Thai AirAsia – 370 flights every day
52 – Frontier Airlines – 362 flights every day
53 – Malaysia Airlines – 361 flights every day
54 – Iberia – 356 flights every day
55 – Virgin Australia – 355 flights every day
56 – Vietnam Airlines – 353 flights every day
57 – Batik Air – 352 flights every day
58 – Ethiopian Airlines – 350 flights every day
59 – Jetstar – 350 flights every day
60 – Spring Airlines – 348 flights every day
61 – VietJet Air – 347 flights every day
62 – Philippine Airlines – 343 flights every day
63 – SAS – 335 flights every day
64 – Ravn Alaska – 334 flights every day
65 – Juneyao Airlines – 323 flights every day
66 – TAP Portugal – 313 flights every day
67 – Cebu Pacific Air – 310 flights every day
68 – Gestair – 307 flights every day
69 – Eurowings – 305 flights every day
70 – Shanghai Airlines – 302 flights every day
71 – Aer Lingus – 299 flights every day
72 – GoAir – 295 flights every day
73 – Citilink – 293 flights every day
74 – LOT – Polish Airlines – 281 flights every day
75 – Beijing Capital Airlines – 276 flights every day
76 – Interjet – 274 flights every day
77 – Aerolineas Argentinas – 273 flights every day
78 – Cape Air – 259 flights every day
79 – South African Airways – 255 flights every day
80 – Lucky Air – 253 flights every day
81 – Sriwijaya Air – 252 flights every day
82 – Copa Airlines – 251 flights every day
83 – Tianjin Airlines – 251 flights every day
84 – Norwegian Air Shuttle – 243 flights every day
85 – Hawaiian Airlines – 241 flights every day
86 – SWISS – 240 flights every day
87 – Allegiant Air – 236 flights every day
88 – Etihad Airways – 232 flights every day
89 – Austrian – 229 flights every day
90 – Tropic Air – 226 flights every day
91 – Air Europa – 224 flights every day
92 – Finnair – 220 flights every day
93 – AirAsia India – 220 flights every day
94 – Cathay Pacific – 218 flights every day
95 – Jet2 – 216 flights every day
96 -Singapore Airlines – 211 flights every day
97 – Maya Island Air – 209 flights every day
98 -Vistara – 204 flights every day
99 -Jeju Air – 203 flights every day
100 – EgyptAir – 199 flights every day

Click HERE to see the Largest airlines in the world page on Wikipedia