Which of the following is true about tetanus acquired through traumatic wound ?

Which of the following is true about tetanus acquired through traumatic wound ?

A. Clostridium tetani travels via the nerves to the anterior horn dells in sal cord
B. The tetanospasmin component of the exotoxin act on the post-synaptic neurones and prevents impulse transmission
C. The patient should be given tetanus toxoid intravenously
D. Causes positive Nagler reaction

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