Select the drug that undergoes extensive first-pass metabolism in the liver:
A. Phenobarbitone
B. Propranolol
C. Phenylbutazone
D. Theophylline
A. Phenobarbitone
B. Propranolol
C. Phenylbutazone
D. Theophylline
A. A constant amount of the drug will be eliminated per unit time
B. Its clearance value will remain constant
C. Its elimination half life will increase with dose
D. It will be completely eliminated from the body in
2 × half life period
A. Ultraviolet absorbance or refractive index measurement.
B. Increase in temperature
C. Ionization in flame
D. Thermal conductivity
A. Lipid solubility
B. Plasma protein binding
C. Degree of ionization
D. Rate of tubular secretion
A. Light source Detector Sample cell Monochromator Readout
B. Light source Sample cell Detector Monochromator Readout
C. Light source Readout Sample cell Detector Monochromator
D. None of these
A. Muscle dystonia caused by triflupromazine
B. Insomnia after taking pentobarbitone
C. Precipitation of asthma by morphine
D. Gum hyperplasia caused by phenytoin
A. hot solids
B. excited polyatomic molecules
C. molecules in the ground molecular state
D. excited atoms