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In acute inflammation, immediate transient permeability in cells is increased by__________?

/ Immunity And Hypersensitivity, Inflammation, Medical Mcqs, Pathology / By
In acute inflammation, immediate transient permeability in cells is increased by__________?

A. Direct injury & necrosis
B. Endothelial Gaps by histamine
C. Leucocyte mediated endothelial injury
D. Increased tissue oncotic pressure