Monoclonal Antibodies

Question: Helper T cells assist in the functions of
[A].

certain B cells

[B].

certain T cells

[C].

certain B cells and other T cells

[D].

none of the above

Answer: Option C

Explanation:

No answer description available for this question.

Question: In immuno-inflammatory diseases such as hemolytic anaemia, eczema etc.,
[A].

T8 cells are greatly reduced

[B].

T8 cells are greatly increased

[C].

T4 cells are greatly reduced

[D].

T4 cells are greatly increased

Answer: Option A

Explanation:

No answer description available for this question.

Question: A cytokine that stimulates the activity of B and T cells is
[A].

lymphotoxin

[B].

interlukin-2

[C].

interlukin-1

[D].

all of these

Answer: Option B

Explanation:

No answer description available for this question.

Question: In human B cells and T cells are matured in the
[A].

bone marrow and thymus respectively

[B].

lymph nodes and spleen respectively

[C].

bursa and thymus respectively

[D].

none of these

Answer: Option A

Explanation:

No answer description available for this question.

Question: An example of mosaic antigen is
[A].

virus

[B].

bacteria

[C].

a hapten

[D].

protein

Answer: Option A

Explanation:

No answer description available for this question.

Question: The approach (s), which is/are currently followed to produce human monoclonal antibodies, is/are known as
[A].

transformation of antigen specific B lymphocytes (EBV)

[B].

hybridization of 6-thioguanine-resistant human plasmacytoma with immune human lymphocytes

[C].

combination of EB Vand hybridoma techniques

[D].

all of these

Answer: Option D

Explanation:

No answer description available for this question.

Question: It is highly valued if the lymphocytes derived from the lymph node or tonsil tend to undergo fusion at
[A].

high frequencies

[B].

moderate frequencies

[C].

low frequencies

[D].

at no frequency

Answer: Option A

Explanation:

No answer description available for this question.

Question: The antigen-specific lymphocytes can be immortalized by which of the following method?
[A].

Transfection with tumor derived DNA

[B].

Hybridization with a suitable lymphoid tumor cell

[C].

Transformation following infection by Epstein-Barr virus (EB V)

[D].

All of the above

Answer: Option D

Explanation:

No answer description available for this question.

Question: In monoclonal antibody technology, tumor cells that can replicate endlessly are fused with mammalian cells that produce an antibody. The result of this cell fusion is a
[A].

hybridoma

[B].

myeloma

[C].

natural killer cell

[D].

lymphoblast

Answer: Option A

Explanation:

No answer description available for this question.