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Within the RBC hypoxia stimulates glycolysis by which of the following regulating pathways ?

Within the RBC hypoxia stimulates glycolysis by which of the following regulating pathways ?

A. Hypoxia stimulates pyruvate dehydrogenase by increased, 2, 3DPG
B. Hypoxia inhibits hexokinase
C. Hypoxia stimulates release of all glycolytic enzymes from Band 3 on RBC membrane
D. Activation of the regulatory enzymes by high PH